When taking Synext, especially on an empty stomach, some users may experience an itchy, tingling, or hot feeling accompanied by red flushes on the skin (flushing). This is a normal and harmless reaction, also called “Niacin flush” and it is beneficial to the skin. This should not be mistaken as an allergic reaction. Any flushing or irritation will dissipate naturally after 5 to 20 minutes. Drinking water will help to reduce the effects of flushing or irritation faster. To reduce instances of side effects we recommend taking Synext with or immediately after meals. Your body’s tolerance for the effects of Synext will increase over time. After the period of conditioning, instances of flushing or irritation should reduce substantially. The next generation of NAD+ supplement – Synext tablets supplement nicotinamide adenine dinucleotide (NAD+) precursors which can be metabolised into NAD+ after administration. NAD+ is essential to cell metabolism and energy generation, involving in over 400 reactions in the body. NAD+ precursors may help maintain healthy NAD+ levels during aging. According to the latest research, our body produces senescent cells which cease to grow or divide and our immune system removes these cells. During aging, our immune system becomes compromised and cannot clear the senescent cells effectively. As a result, they may accumulate and cause aging-related health issues, especially problems with the heart and bones. Synext has included a new combination of ingredients that support heart function and protect bones. Combining with other potent antioxidants, Synext tablets synergistically combat the aging process and reduce free radicals formed in the body. The result for Dietary Supplements differs depending on physical condition. If symptoms persist, please see your healthcare professionals.